Beth grew up in Riverside, Connecticut. She received her undergraduate degree in Chemical Engineering from the University of Notre Dame. After graduating, she joined Dr. Eugene Major's lab at NINDS, where she studied the interactions between B cell transcription factors and JC virus, the etiological agent of the fatal demyelinating disease, progressive multifocal leukoencephalopathy (PML). In 2012, she joined Dr. Jeffrey Rothstein's lab at Johns Hopkins, where she contributed to findings which identified RNA toxicity and nucleocytoplasmic transport defects as key phenotypes in mutant C9orf72 ALS patient neurons. In 2015, she joined NUIN as a graduate student. For her thesis, Beth is interested in uncovering proteome-wide nucleocytoplasmic changes in C9orf72-related ALS, advancing our understanding of RNA degradation defects in C9orf72-related ALS, and identifying how mutations in a novel ALS-related gene, NEK1, cause motor neuron dysfunction. In her spare time, Beth likes to play squash, read, and watch college football. (Go Irish!)
The lab is superbly located in the downtown Chicago area, a few minutes away from Lake Michigan,
the shopping and restaurants of Magnificent Mile, within the historical Montgomery Ward Memorial Building.
For general lab inquires please contact our lab manager Kevin at: Phone: 312-503-6126 | E-mail: kevin.smith@northwestern.edu